Abstract
Burkitt's lymphoma (BL) is a heterogeneous group of highly aggressive mature B-cell malignancies. It is characterized by a high rate of turnover of malignant cells and deregulation of the c-myc gene. It is typically associated with a t(8;14) translocation. Dual translocation of t(8;14) (c-myc) and t(14;18) (bcl-2) was reported to be associated with extremely poor prognosis. This study reports a novel t(8;14;18) triple translocation in two patients with Burkitt's lymphoma. © 2007 Liu et al; licensee BioMed Central Ltd.
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CITATION STYLE
Liu, D., Shimonov, J., Primanneni, S., Lai, Y., Ahmed, T., & Seiter, K. (2007). t(8;14;18): A 3-way chromosome translocation in two patients with Burkitt’s lymphoma/leukemia. Molecular Cancer, 6. https://doi.org/10.1186/1476-4598-6-35
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