Memory Lymphocyte Clusters in Genital Immunity: Role of Tissue-Resident Memory T Cells (TRM)

Abstract

Development of front-line defenses in genital tissues is important to inhibit viral/bacterial replication and to eliminate sexually transmitted diseases. In this chapter, we discuss the cellular composition, location, and function of memory lymphocyte clusters deployed in mucosal tissues and compare them with those in secondary lymphoid organs and tertiary lymphoid structures.