Human Wound Healing Ex Vivo Model with Focus on Molecular Markers

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Abstract

Wound healing is a complex, multifactorial process that is divided in sequential and overlapping phases in order to restore the skin barrier. For the study of wound healing, different in vivo, in vitro, and ex vivo models have been used in the past. Here we describe in detail the methodology of the human skin punch-in-a-punch ex vivo wound healing model.

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Gherardini, J., van Lessen, M., Piccini, I., Edelkamp, J., & Bertolini, M. (2020). Human Wound Healing Ex Vivo Model with Focus on Molecular Markers. In Methods in Molecular Biology (Vol. 2154, pp. 249–254). Humana Press Inc. https://doi.org/10.1007/978-1-0716-0648-3_21

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