Biosynthetic potential of hairy roots for production of new natural products

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Abstract

Metabolite profile of transgenic roots may differ from that of parental plant, but this feature is not necessarily a disadvantage. The review focuses on new substances produced in hairy roots as a result of tumorous root formation by itself or in combination with different treatments and/or genetic engineering manipulations. Examples of new secondary metabolites from hairy root cultures, not known in parental plants, and products of heterologous gene expression are described. In our opinion, transgenic roots may be regarded as a promising origin of natural product biodiversity.

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Sheludko, Y., & Gerasymenko, I. (2013). Biosynthetic potential of hairy roots for production of new natural products. In Biotechnology for Medicinal Plants: Micropropagation and Improvement (Vol. 9783642299742, pp. 241–262). Springer-Verlag Berlin Heidelberg. https://doi.org/10.1007/978-3-642-29974-2_10

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