Multi-omics analysis reveals the associations between altered gut microbiota, metabolites, and cytokines during pregnancy

  • Huang T
  • Liang X
  • Bao H
  • et al.
6Citations
Citations of this article
18Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

A great number of studies have focused on diseases induced by intestinal microecological disorders and immune imbalances. However, the understanding of how intestinal microbiota interacts with immunity during normal pregnancy, which is fundamental to studying pathological pregnancies related to intestinal microbiota disturbances, has not been well elucidated. Our study employed multi-omics analysis to discover that changes in gut microbiota and metabolites during pregnancy can impact immune function. In addition, we identified several metabolites that may mediate the effect of gut microbes on plasma cytokines. Our study offered new insights into our understanding of the connections between the gut microbiome, metabolome, and the immune system during pregnancy.

Cite

CITATION STYLE

APA

Huang, T., Liang, X., Bao, H., Ma, G., Tang, X., Luo, H., & Xiao, X. (2024). Multi-omics analysis reveals the associations between altered gut microbiota, metabolites, and cytokines during pregnancy. MSystems, 9(3). https://doi.org/10.1128/msystems.01252-23

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free