0851 Social Jetlag And The Increased Risk Of Anemia: Data From The Korea National Health And Nutrition Examination Survey VII

Abstract

The discrepancy between social and biological time, described as ‘social jetlag’,can be estimated by the difference in mid-sleep time during the weekend and during weekdays. Social jetlag is known to increase risk of metabolic complications, heart disease and other problems. Anemia is associated with sleep related conditions such as night sleep duration and sleep quality. In this study, we aimed to evaluate the association between social jet lag and anemia.We analyzed adult participants (age ≥19) of the seventh Korea national health and nutrition examination survey (KNHANES VII, 2016). Shift workers were excluded from the analysis. The association between social jetlag and a low hemoglobin level, defined as hemoglobin <12 g/dL was analyzed using multivariable logistic regression.A total of 5146 participants were included in the analysis. Mean age of the study population was 51.8 (SD 16.7), and 2983 (58%) were women. Anemia was found in411 (9%) of the subjects. After adjusting for age, sex, job status, body mass index, hypertension, diabetes, hyperlipidemia, smoking, and alcohol consumption, social jetlag of more than 1 hour had an increased risk of low hemoglobin level with an odds ratio (OR) of 1.47 (95% confidence interval (CI),1.01-2.06; p = 0.03). The association was stronger in women (OR 1.53, 95% CI1.06-2.17, p = 0.02) but not significant in men.These results suggest that social jetlag is associated with a higher risk of anemia. This study warrants further investigations on the effect of social jetlag and anemia-related health conditions.None