Relationship Among Blood Boron Level, Diabetes Mellitus, Lipid Metabolism, Bone Metabolism and Obesity: Can Boron Be An Efficient Indicator for Metabolic Dissesases?

Abstract

This study targeted at investigating the possibility of association between blood boron (B) level and charbohydrate and lipid metabolisms and bone structuring metabolites and using B as an indicator of obesity and certain diseases as Diabetes Mellitus type II. 42 patients categorized under control, diabetic and obese diabetic groups of 14 subjects (7 male and 7 female) of different age volunteered in the study. Pronounced negative correlation was observed between serum B level and glucose level of female and male subjects in diabetic (r=-0.653; -0.567) and obese diabetic (r=-0.715; -0.748) and HbA1c levels in diabetic (r=-0.452; -0.367) and obese diabetic (r=-0.648; -0.542) groups but no meaningful relation could be established neither with insulin nor with HDL levels. Triglyceride values showed negative correlation in diabetic female (r=-0.483) and obese diabetic male (r=-0.612) groups and so did total cholesterol in diabetic (r=-0.412; -0.541) and obese diabetic (r=-0.578; -0.674) female and male subjects. Vitamin D levels in diabetic (r=0.350; 0.586) and obese diabetic (r=-0.241; 0.453) female and male subjects showed positive correlation. Findings indicated that B level can be a good indicator of diseases related with carbohydrate, lipid and bone metabolisms.