500 mg as bolus followed by an extended infusion of 1500 mg of meropenem every 8 h failed to achieve in one-third of the patients an optimal PK/PD against non-resistant strains of these organisms: is CRRT responsible for this situation?

Honore, P. M., Barret Gutierrez, L., Kugener, L., Redant, S., Attou, R., Gallerani, A., & De Bels, D. (2020, December 1). 500 mg as bolus followed by an extended infusion of 1500 mg of meropenem every 8 h failed to achieve in one-third of the patients an optimal PK/PD against non-resistant strains of these organisms: is CRRT responsible for this situation? Annals of Intensive Care. Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1186/s13613-020-00777-2