The Use of Neuronal Response Signals as Early Biomarkers of Dyslexia

Abstract

Objectives: Brain imaging techniques have broadened our understanding of structural and functional properties of neuronal networks in children with developmental disabilities. The present work examines current models of neuronal response properties implicated in dyslexia and reading difficulties. Methods: This review analyzes the use of functional techniques (fMRI and EEG) employed in the assessment of neuronal markers associated with reading ability. Results: Neuro-imaging studies have provided evidence of neuronal networks involved in the emergence of reading fluency. Using this information, it is now possible to employ physiological assessments in the screening of reading ability before behavioral evaluations can be conducted. Conclusions: Analyses of neuro-imaging studies show that abnormal neuronal activation in specific brain areas can be used to help identify reading impairments in children. These neuronal assessments permit earlier identification of dyslexia than those requiring behavioral assessments.