Deciphering gene regulatory networks requires the systematic identification of functional cis-acting regulatory elements. We present a suite of web-based bioinformatics tools, called GeneACT http://promoter.colorado.edu, that can rapidly detect evolutionarily conserved transcription factor binding sites or microRNA target sites that are either unique or over-represented in differentially expressed genes from DNA microarray data. GeneACT provides graphic visualization and extraction of common regulatory sequence elements in the promoters and 3′-untranslated regions that are conserved across multiple mammalian species. © 2006 Cheung et al.; licensee BioMed Central Ltd.
CITATION STYLE
Cheung, T. H., Kwan, Y. L., Hamady, M., & Liu, X. (2006). Unraveling transcriptional control and cis-regulatory codes using the software suite GeneACT. Genome Biology, 7(10). https://doi.org/10.1186/gb-2006-7-10-r97
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