AllerGen’s 8th research conference

Abstract

The proceedings contain 35 papers. The topics discussed include: early life intestinal microbial alterations are associated with pediatric asthma in rural Ecuador; cellular mechanisms involved in the allergic lung response to the environmental bioaerosol archaea methanosphaera stadtmanae; climate change, asthma and allergy risk in Toronto; distinct trajectories in depressive symptoms and perceived stress from pregnancy to the postnatal period; the effects of birth weight on infant pulmonary function; immune genes are differentially methylated in relation to early life stress exposure; lung clearance index (LCI) in 3 year old children with clinically assessed preschool asthma; longitudinal measures of DNA methylation associated with alcohol exposure cessation in purified t-lymphocytes; resiquimod (S28463) treatment prevents the increase in airway resistance and decreases inflammation and serum IgE levels in ascaris suum induced allergic asthma model in non-human primates; airway epithelial production of IL-17C in response to bacterial and rhinovirus co-exposure; linking the indoor microbiome with atopy in the CHILD study: preliminary findings; maternal depression during pregnancy and 4-month infant gut immunoglobulin a levels; and integration of transcriptomics, proteomics and genome-wide association studies (GWAS) with network analyst to gain insights into innate immunity.