ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (ST6GALNAC1)

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Abstract

ST6GalNAc-I is a CMP-sialic acid, N-acetylgalactosaminide α2-6-sialyltransferase (GalNAcα2-6-sialyltransferase), that transfers sialic acid from CMP-sialic acid (CMP-Sia) to the N-acetylgalactosamine residues of glycoconjugates through an α2,6-linkage. Like other sialyltransferases, ST6GalNAc-I exhibits type II membrane protein topology and is classified into CAZy glycosyltransferase family 29 (Coutinho et al. 2003).

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Tsuji, S., & Takashima, S. (2014). ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (ST6GALNAC1). In Handbook of Glycosyltransferases and Related Genes, Second Edition (Vol. 2, pp. 715–725). Springer Japan. https://doi.org/10.1007/978-4-431-54240-7_144

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