Objective To analyze the relationship between alcohol consumption and incident HIV infection. Methods Articles were identified via electronic and hand searches. Inclusion criteria were: incident HIV infection, preceding alcohol consumption, and association relating the two. The DerSimonian and Laird random effects model was used. For studies with more than one estimate of a given type, estimates were combined using the inverse variance weighted method. Publication bias was assessed using Begg's and Egger's tests. Heterogeneity was assessed using Q and I2 statistics. Results Ten studies were included. Overall alcohol consumption (any of the three types identified) increased the risk of HIV (RR 1.98, 95% CI 1.59-2.47). Alcohol consumers were at 77% higher risk (RR 1.77, 95% CI 1.43-2.19). Those consuming alcohol prior to, or at the time of, sexual relations were at an 87% increased risk (RR 1.87, 95% CI 1.39-2.50). For binge drinkers, the risk was double that of non-binge drinkers (RR 2.20, 95% CI 1.29-3.74). Conclusions Alcohol consumption is associated with an increased risk of incident HIV infection. Additional research is required to further investigate a possible causal role. © Birkhäuser Verlag, Basel/Switzerland 2009.
CITATION STYLE
Baliunas, D., Rehm, J., Irving, H., & Shuper, P. (2010). Alcohol consumption and risk of incident human immunodeficiency virus infection: A meta-analysis. In International Journal of Public Health (Vol. 55, pp. 159–166). Birkhauser Verlag Basel. https://doi.org/10.1007/s00038-009-0095-x
Mendeley helps you to discover research relevant for your work.