Obesity is associated with increased morbidity but not mortality in critically ill patients

133Citations
Citations of this article
95Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Objective: To investigate the possible impact of obesity on morbidity and mortality in intensive care unit (ICU) patients included in the European observational sepsis occurrence in acutely ill patients (SOAP) study. Design: Planned substudy from the SOAP database. Setting: One hundred and ninety-eight ICUs in 24 European countries. Patients: All patients admitted to one of the participating ICUs. Patients were classified, according to their body mass index (BMI), as underweight (<18.5 kg/m2), normal weight (18.5-24.9 kg/m2), overweight (25-29.9 kg/m2), obese (30-39.9 kg/m2), and very obese (≥40 kg/m2). Measurements and results: The BMI was available in 2,878 (91%) of the 3,147 patients included in the SOAP study; 120 patients (4.2%) were underweight, 1,206 (41.9%) had a normal BMI, 1,047 (36.4%) were overweight, 424 (14.7%) were obese, and 81 (2.8%) were very obese. Obese and very obese patients more frequently developed ICU-acquired infections than patients in lower BMI categories. Very obese patients showed a trend towards longer ICU [median (IQ): 4.1 (1.8-12.1) vs. 3.1 (1.7-7.2) days, P = 0.056) and hospital lengths of stay [14.3 (8.4-27.4) vs. 12.3 (5.1-24.4), days P = 0.077] compared to those with a normal BMI. However, there were no significant differences among the groups in ICU or hospital mortality rates. In a multivariate Cox regression analysis, none of the BMI categories was associated with an increased risk of 60-day in-hospital death. Conclusion: BMI did not have a significant impact on mortality in this mixed population of ICU patients. © 2008 Springer-Verlag.

Cite

CITATION STYLE

APA

Sakr, Y., Madl, C., Filipescu, D., Moreno, R., Groeneveld, J., Artigas, A., … Vincent, J. L. (2008). Obesity is associated with increased morbidity but not mortality in critically ill patients. Intensive Care Medicine, 34(11), 1999–2009. https://doi.org/10.1007/s00134-008-1243-0

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free