Further evidence of spontaneous cure in human Chagas disease

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Abstract

An acute case of Chagas disease was studied in 1944, with clinical and laboratory follow-up until 2007, in Bambuí, Minas Gerais, Brazil. A five-year-old girl living in a rural hut that was highly infested with Triatoma infestans presented a febrile clinical condition compatible with the acute form of trypanosomiasis. She presented a positive thick blood smear, but never again showed serological and/or parasitological evidence of Trypanosoma cruzi infection, on several occasions. This patient never received any specific treatment and, to this day, she remains completely asymptomatic, with normal findings from clinical, electrocardiographic, X-ray and echocardiographic examinations.

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Dias, J. C. P., Dias, E., Filho, O. M., Vitelli-Avelar, D., Correia, D., Lages, E., & Prata, A. (2008). Further evidence of spontaneous cure in human Chagas disease. Revista Da Sociedade Brasileira de Medicina Tropical, 41(5), 505–506. https://doi.org/10.1590/S0037-86822008000500014

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