Elastic fibers are an essential and irreplaceable structural component of lung tissue, blood vessels, and skin. Degradation of elastic fibers in these organs results in emphysema, aortic aneurysm, and solar elastosis (aging skin), respectively. Enzymes capable of degrading elastin have been termed elastases. This chapter will discuss the properties of the elastases, discuss the consequences of elastic fiber breakdown (elastolysis), and review the emerging reports of nonelastolytic functions of elastases in health and disease.
CITATION STYLE
Houghton, A. M., Mouded, M., & Shapiro, S. D. (2011). Consequences of Elastolysis. In Extracellular Matrix Degradation (pp. 217–249). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-16861-1_9
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