Gamma Knife: Technical Aspects

Abstract

Lars Leksell designed the Gamma Knife® unit (Figure 58-1 ) from the ground up to be a tool of the neurosurgeon. The physics and engineering choices inherent in the design of the unit is perhaps best considered from the perspective of a surgeon end-user. Of all of the radiosurgical tools, the Gamma Knife is the oldest and best established. Since its first conception by Lars Leksell and Börje Larsson, the system has evolved through several generations of improvements; however the basic principles of the instrument remain primarily unchanged. This chapter will describe the physical principles and method of operation of the Gamma Knife, paying particular attention to the new features and changes found in the recently released Leksell Gamma Knife® Perfexion™.