Oxidative stress may contribute to the progression of chronic renal failure. In this study, cats with spontaneous renal insufficiency were fed a dry cat food supplemented with the antioxidants vitamins E and C, and β-carotene for 4 weeks. When compared with healthy cats, cats with renal insufficiency had a tendency to oxidative stress. The antioxidant supplements significantly reduced DNA damage in cats with renal insufficiency as evidenced by reduced serum 8-OHdG and comet assay parameters. Therefore, supplements of vitamins E and C and β-carotene as antioxidants may be beneficial to cats with renal disease. © Springer Science+Business Media, Inc. 2006.
CITATION STYLE
Yu, S., & Paetau-Robinson, I. (2006). Dietary supplements of vitamins E and C and β-carotene reduce oxidative stress in cats with renal insufficiency. Veterinary Research Communications, 30(4), 403–413. https://doi.org/10.1007/s11259-006-3269-5
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