Giving TRALI the one-two punch

Abstract

In this issue of Blood, Toy et al identify recipient and blood product factors associated with increased risk of transfusion-associated acute lung injury (TRALI) using data derived from the largest active surveillance, prospective, case-controlled study.1 This study provides important new insights into our mechanistic understanding of an important clinical problem in transfusion medicine and validates the effectiveness of TRALI mitigating strategies that have been implemented.