Koinfeksi Sifilis Sekunder, Condyloma Acuminata dan Human Immundeficiency Virus (HIV) pada Pria Homoseksual

  • Ahmad Fiqri
  • Endra Yustin ES
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Abstract

Introduction: Men who have sex with men (MSM) have higher risk of contracting sexually transmitted infections (STIs) such as syphilis, one of chronic and systemic STI. HIV and HPV infection can be risk factors for syphilis infection, while coinfection between syphilis and HIV facilitates the course of the two diseases. Case: A 22-year-old homosexual man complained of red scaly patches on both palms and feet, no itching, hair loss and lumps in the genital area. Examination revealed nonscarring alopecia on occipital region, bilateral patches with multiple erythematous plaques partly confluent hyperpigmentation and an overlying scale on palmar and plantar region, also multiple nodule papules with pale red smooth surface on perineal region. The acetowhite examination at the verrucous lesion was positive. The results of the CD4 examination was 112 cells/µl, VDRL/RPR was reactive 1:256; and TPHA was also reactive >1:5,120. Histopathological examination of the skin showed the features of skin syphilis and condyloma acuminata. Immunohistochemistry test revealed brownish Spirochaeta. The patient was diagnosed with secondary syphilis coinfection, condyloma acuminata, and HIV. Conclusion: We found a case of MSM patient that was coinfected with secondary syphilis, condyloma acuminata, and HIV. HPV and HIV infection are often coexisting because they both increase the risk of sexually transmitted infections.Pendahuluan: Pria homoseksual merupakan kelompok yang berisiko tinggi terkena infeksi menular seksual (IMS). Sifilis merupakan salah satu jenis IMS yang bersifat kronis dan sistemik. Infeksi virus human immunodeficiency virus (HIV) dan atau human papillomavirus (HPV) merupakan faktor risiko terjangkitnya infeksi sifilis, dan infeksi HIV serta koinfeksi sifilis dapat saling meningkatkan risiko IMS lainnya. Kasus: Seorang laki-laki 22 tahun, orientasi seksual sesama jenis, mengeluh bercak merah bersisik di kedua telapak tangan dan kaki, tidak gatal, rambut rontok, dan benjolan di daerah genital. Pemeriksaan regio oksipital tampak adanya alopesia tanpa disertai jaringan parut, regio palmar dan plantar pedis bilateral tampak patch, plak eritem multipel sebagian hiperpigmentasi konfluens dengan skuama di atasnya, dan pada regio perineal tampak papul nodul multipel dengan permukaan licin merah pucat. Pemeriksaan acetowhite positif pada lesi papul verukosa. Hasil pemeriksaan CD4 112 sel/µl, VDRL/RPR reaktif 1:256, dan TPHA reaktif >1:5.120. Gambaran histopatologi kulit sesuai dengan gambaran sifilis kulit dan condyloma acuminata. Pada pemeriksaan imunohistokimia, didapatkan gambaran Spirochaeta berwarna kecoklatan. Pasien didiagnosis dengan koinfeksi sifilis sekunder, condyloma acuminata, dan HIV. Kesimpulan: Pada kasus ini didapatkan seorang pasien homoseksual dengan koinfeksi sifilis sekunder, condyloma acuminata dan HIV. Infeksi HPV dan HIV sering ditemukan bersamaan, dan keduanya saling meningkatkan risiko infeksi menular seksual.

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Ahmad Fiqri, & Endra Yustin ES. (2022). Koinfeksi Sifilis Sekunder, Condyloma Acuminata dan Human Immundeficiency Virus (HIV) pada Pria Homoseksual. MEDICINUS, 35(2), 20–30. https://doi.org/10.56951/medicinus.v35i2.94

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