Ophthalmic manifestations of acute leukaemias

Abstract

Background and aims: To determine the incidence of ocular pathological findings in a group of patients with acute leukemia. To define the predictive value of the presence of the ocular pathological findings. Materials and methods: Retrospective evaluation of a group of 67 patients with acute leukemia (age 1–75 years) examined at the Ophthalmology Clinic, Faculty Hospital Ostrava, from 2005 to 2014. Results: Ocular pathological findings were found in 13 patients of the group (19.4 %)-7 patients with acute myeloid leukemia (10.9 %) and 6 patients with acute lymphoblastic leukemia (8.5 %). 10 patients died due to of the underlying disease. Ocular pathological findings were found in 6 of them (60 %). A higher prognostic value was found in a group of patients with AML. Conclusion: Ophthalmology examination is a necessary part of the examination of patients with acute leukemia. This prognostic benefit is particularly significant in patients with AML.