Continuous solid-state fermentation bioreactors

Abstract

The previous chapters have presented solid-state fermentation (SSF) bioreactors that operate in batch mode. Although batch operation is the most common type of operation in SSF processes to date, it is also possible to design and operate continuous SSF bioreactors. However, there are challenges faced in the operation of continuous SSF bioreactors that are not faced in classical continuous submerged liquid fermentation (SLF) processes and, consequently, true continuous-flow SSF bioreactors (CSSFBs) are currently scarce in industry. Improved design procedures and sensors promise a better future for these bioreactors. This chapter deals with the design and operation of continuous SSF bioreactors and discusses the potential advantages that continuous operation can bring to SSF processes and also the various considerations that need to be addressed in order to arrive at a well-performing continuous process. © Springer-Verlag Berlin Heidelberg 2006.