Poly(dA:dT) make it and break it

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Abstract

Poly(dA:dT) tracts characterize strong DNA replication origins in mammals and cause replication-fork collapse and DNA breaks that underlie the expression of fragile sites.

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Zlotorynski, E. (2018, October 1). Poly(dA:dT) make it and break it. Nature Reviews Molecular Cell Biology. Nature Publishing Group. https://doi.org/10.1038/s41580-018-0054-6

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