Breast lesion analysis of shape technique: Semiautomated vs. manual morphological description

Abstract

Purpose: To investigate the efficacy of an automated method of shape measurement for improving the discrimination of benign and malignant breast lesions. Materials and Methods: A total of 47 breast lesions (32 malignant and 15 benign) were examined using a 1.5 Tesla system. Regions of interest (ROIs) were manually drawn and extracted from high-resolution, fat-suppressed, post-contrast images, or were extracted with the use of a semiautomated computer algorithm. Shape parameters (i.e., complexity, convexity, circularity, and degree of elongation) were determined to assess whether they could be used to discriminate breast lesions. Results: Convexity differed significantly between the benign and malignant groups for both ROI methods. In addition, the semiautomated method demonstrated significantly different values of complexity. Conclusion: This work demonstrates the usefulness of several shape descriptors for characterizing breast lesions, and shows that the automated method of analysis improves the discrimination and standardization of data. © 2006 Wiley-Liss, Inc.