Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: Case reports and a review

Abstract

We present a case of Stevens Johnson syndrome in a child after carbamazepine application and Stevens Johnson/TEN overlap syndrome in an adult after amoxicillin application. On the basis of two reported cases we review the most commonly associated drugs, the postulated pathogenesis, clinical manifestation and management in these severe life-threatening diseases. We especially discuss the controversial systemic corticosteroid therapy. Topical care is also discussed. Copyright © 2010 Termedia & Banach.