IN-VITRO ANTIVIRAL ACTIVITY OF PISTACIA CHINENSIS FLAVONOIDS AGAINST HEPATITIS C VIRUS (HCV)

Abstract

The present study was designed to evaluate anti-HCV activity of Pistacia chinensis aerial parts and identify the responsible bioactive constituents of anti-hepatitis ethnomedicinal plant P. chinensis methanol 80% extract. This has led to the isolation and characterization of gallic acid and eight flavonoids, apigenin, diosmetin, myricetin, apigenin 7-O-β-glucoside, quercetin 3-O-β-glucoside myricetin 3-O-α-rhamnoside, myricetin 3-O-β-glucuronide and quercetin 3-O-β-glucoside-7-O-α-rhamnoside from the plant, using various chromatographic procedures and the interpretation of spectral data in comparison with already existing data reported in the literature.