Composite scaffolds for bone regeneration made of collagen/hydroxyapatite/eucalyptus essential oil

Abstract

Bone regeneration is a serious problem nowadays because of the increased number of people suffering from infections, arthritis and bond loss. The aim of the present study was to develop and characterize collagen – hydroxyapatite – essential oil matrices for bone regeneration. In our study we wish to develop biomaterials which mimic bone composition and prevent allergic or toxic effects. The matrices obtained by freeze-drying were characterized by FT-IR analysis, water uptake capacity and microbiological analysis. The results obtained from analyses confirmed that collagen–hydroxyapatite-essential oils matrices exhibit proper characteristics for bone regeneration.