Break-up analysis of the tear film based on time, location, size and shape of the rupture area

Abstract

The Break-Up Time test (BUT) evaluates the quality and stability of the tear film. It is used for the diagnosis of the dry eye syndrome, a common disorder of the tear film, affecting a significant percentage of the population. This work describes a fully automatic methodology to compute the time in which the break-up occurs and to analyze the rupture zone. This analysis provides useful quantitative and qualitative information for the clinical practice about the location, size and shape of the break-up areas. © 2013 Springer-Verlag.