The co-occurrence of a vestibular schwannoma and a low-grade glioma is rare, and even rarer is the association with an oligodendroglioma. Although various authors have addressed the problem of treating patients with incidentally discovered indolent low-grade gliomas, an established protocol does not exist to date. The common approach is to reserve surgery until there is radiological evidence of tumor growth or high-grade transformation. However, because incidental low-grade glioma may represent the first stage of unavoidable pathological progression towards high-grade glioma, early and radical surgical resection should be advocated in order to increase the chance of a "cure" and prolonged survival. This case report supports this view, and suggests refection on a possible change from a conservative philosophy to preventative surgical treatment. © 2012 Iacoangeli et al, publisher and licensee Dove Medical Press Ltd.
CITATION STYLE
Iacoangeli, M., Di Rienzo, A., Colasanti, R., Alvaro, L., Nocchi, N., Polonara, G., … Scerrati, M. (2012). Rare synchronous association of vestibular schwannoma and indolent insular oligodendroglioma in a patient without neurofbromatosis: Controversial issue of timing for surgical treatment of asymptomatic low-grade gliomas. OncoTargets and Therapy, 5, 357–361. https://doi.org/10.2147/OTT.S39276
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