Community-acquired pyelonephritis in pregnancy caused by KPC-producing Klebsiella pneumoniae

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Abstract

Carbapenem-resistant Enterobacteriaceae (CRE) usually infect patients with significant comorbidities and health care exposures. We present a case of a pregnant woman who developed community-acquired pyelonephritis caused by KPC-producing Klebsiella pneumoniae. Despite antibiotic treatment, she experienced spontaneous prolonged rupture of membranes, with eventual delivery of a healthy infant. This report demonstrates the challenge that CRE may pose to the effective treatment of common infections in obstetric patients, with potentially harmful consequences to maternal and neonatal health.

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Khatri, A., Murphy, N. N., Wiest, P., Osborn, M., Garber, K., Hecker, M., … Harris, P. N. A. (2015). Community-acquired pyelonephritis in pregnancy caused by KPC-producing Klebsiella pneumoniae. Antimicrobial Agents and Chemotherapy, 59(8), 4375–4378. https://doi.org/10.1128/AAC.00553-15

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