An in vivo proton magnetic resonance spectroscopy study of schizophrenia patients

94Citations
Citations of this article
47Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

The level of the 1H metabolites in the left dorsolateral prefrontal region of schizophrenia patients at different stages of illness were measured in vivo using a short echo time spectroscopy technique. During both the early onset and chronic stages, normal N-acetylaspartate levels were observed, which suggests that these patients had no significant neuronal cell damage and/or loss. The in vivo measurements of glutamate in the first-episode, drug-naive patients failed to provide convincing evidence for the involvement of the glutamatergic system in the dorsolateral prefrontal region. Significant differences in the glutamine levels were observed in the acutely medicated and chronic patients; however, the interpretation of these differences requires further study.

Cite

CITATION STYLE

APA

Stanley, J. A., Williamson, P. C., Drost, D. J., Rylett, R. J., Carr, T. J., Malla, A., & Thompson, R. T. (1996). An in vivo proton magnetic resonance spectroscopy study of schizophrenia patients. Schizophrenia Bulletin. Oxford University Press. https://doi.org/10.1093/schbul/22.4.597

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free