Response to cimetidine in a 1-year-old child with PFAPA syndrome

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Abstract

Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is characterized by periodic febrile attacks recurring regularly every 2 to 8 weeks. Although tonsillectomy is offered as an effective treatment, the effectiveness of cimetidine treatment is still controversial. In this article, we describe two cases. A 1-year-old girl with PFAPA syndrome received cimetidine treatment and febrile attacks were reduced. Tonsillectomy was successfully performed on a 6-year-old boy with PFAPA syndrome. We suggest that the use of cimetidine may reduce febrile attacks of PFAPA syndrome until an age that is safer for tonsillectomy.

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APA

Taniguchi, K., Ono, N., Sakai, T., Ichiyama, Y., & Uemichi, K. (2017). Response to cimetidine in a 1-year-old child with PFAPA syndrome. Turkish Journal of Pediatrics, 58(6), 687–689. https://doi.org/10.24953/turkjped.2016.06.020

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