Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is characterized by periodic febrile attacks recurring regularly every 2 to 8 weeks. Although tonsillectomy is offered as an effective treatment, the effectiveness of cimetidine treatment is still controversial. In this article, we describe two cases. A 1-year-old girl with PFAPA syndrome received cimetidine treatment and febrile attacks were reduced. Tonsillectomy was successfully performed on a 6-year-old boy with PFAPA syndrome. We suggest that the use of cimetidine may reduce febrile attacks of PFAPA syndrome until an age that is safer for tonsillectomy.
CITATION STYLE
Taniguchi, K., Ono, N., Sakai, T., Ichiyama, Y., & Uemichi, K. (2017). Response to cimetidine in a 1-year-old child with PFAPA syndrome. Turkish Journal of Pediatrics, 58(6), 687–689. https://doi.org/10.24953/turkjped.2016.06.020
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