The importance of being dispersed: A ranking of diffusion MRI models for fibre dispersion using in vivo human brain data

5Citations
Citations of this article
9Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

In this work we compare parametric diffusion MRI models which explicitly seek to explain fibre dispersion in nervous tissue. These models aim at providing more specific biomarkers of disease by disentangling these structural contributions to the signal. Some models are drawn from recent work in the field; others have been constructed from combinations of existing compartments that aim to capture both intracellular and extracellular diffusion. To test these models we use a rich dataset acquired in vivo on the corpus callosum of a human brain, and then compare the models via the Bayesian Information Criteria. We test this ranking via bootstrapping on the data sets, and cross-validate across unseen parts of the protocol. We find that models that capture fibre dispersion are preferred. The results show the importance of modelling dispersion, even in apparently coherent fibres. © 2013 Springer-Verlag.

Cite

CITATION STYLE

APA

Ferizi, U., Schneider, T., Tariq, M., Wheeler-Kingshott, C. A. M., Zhang, H., & Alexander, D. C. (2013). The importance of being dispersed: A ranking of diffusion MRI models for fibre dispersion using in vivo human brain data. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 8149 LNCS, pp. 74–81). https://doi.org/10.1007/978-3-642-40811-3_10

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free