In this study we report the detection of the recently described mcr-4 gene in two human isolates of Salmonella enterica serovar Typhimurium. The strains were isolated from faecal samples of two Italian patients with gastroenteritis, collected in 2016. The identified mcr-4 genes (variant mcr-4.2) differed from the mcr-4 gene originally described in a Salmonella strain of swine origin from Italy. Salmonella species could represent a hidden reservoir for mcr genes.
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Carretto, E., Brovarone, F., Nardini, P., Russello, G., Barbarini, D., Pongolini, S., … Sarti, M. (2018). Detection of mcr-4 positive Salmonella enterica serovar Typhimurium in clinical isolates of human origin, Italy, october to November 2016. Eurosurveillance, 23(2). https://doi.org/10.2807/1560-7917.ES.2018.23.2.17-00821