Abstract
STAT5 is required for IL-7–mediated proliferation and viability, but it does not regulate Bcl-2 downstream from IL-7 in T-ALL cells. PIM1 is required for IL-7-induced leukemia cell cycle progression and proliferation and may be a therapeutic target for IL-7-reliant T-ALLs.
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APA
Ribeiro, D., Melão, A., van Boxtel, R., Santos, C. I., Silva, A., Silva, M. C., … Barata, J. T. (2018). STAT5 is essential for IL-7–mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells. Blood Advances, 2(17), 2199–2213. https://doi.org/10.1182/bloodadvances.2018021063
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