In this elegant study, Evrard et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20210116) find that sphingosine 1-phosphate receptor 5 (S1PR5) powerfully impairs tissue-resident memory T cell (TRM) formation, and that tissue-derived TGF-β limits S1pr5 expression by infiltrating T cells.
CITATION STYLE
Hallisey, V. M., & Schwab, S. R. (2021). Blood-thirsty: S1PR5 and TRM. Journal of Experimental Medicine, 219(1). https://doi.org/10.1084/jem.20211971
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