Despite day-to-day variations in caloric intake and expenditure, the regulation of body weight is precisely controlled over long periods of time. To achieve this objective, the body possesses a wide and complex network of neuroendocrine signals originating in the gastrointestinal system, the central nervous system, and adipose tissue, among other sources to regulate both short- and long-term balances between energy intake and energy expenditure. A better understanding of the central and peripheral factors involved, particularly the role of gut hormones, will pave the way for development of improved treatment modalities for obesity.
CITATION STYLE
Shukla, A. P., Moreira, M., & Rubino, F. (2013). Pathophysiology of obesity. In Bariatric Endoscopy (pp. 11–17). Springer New York. https://doi.org/10.1007/978-1-4419-1710-2_2
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