The technique of gel electrophoresis is now firmly established as a routine laboratory method for analyzing DNA. Here, we describe the development of the methodology as well as a brief explanation of how the technique works. There is a short introduction to pulsed-field agarose gel electrophoresis, which represents a critical advancement in the method that facilitates the analysis of very large fragments of DNA. Finally, theoretical considerations are included. © Springer Science+Business Media, New York 2013.
CITATION STYLE
Roberts, G. A., & Dryden, D. T. F. (2013). DNA electrophoresis: Historical and theoretical perspectives. Methods in Molecular Biology. Humana Press Inc. https://doi.org/10.1007/978-1-62703-565-1_1
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