Differential Functional Summarization

Abstract

In the preceding chapters, we have focused our discussions on clustering and summarizing static biological networks. This limits the power to summarize the complex behavior of a biological network as it is dynamic and responds to both environmental and genetic factors. The complexity associated with understanding the dynamic behavior of biological systems is well known, hence this is a challenging problem that requires careful investigation. To this end, in this chapter we present DiffNet {[}1] towards generating differential functional summary between two snapshots of a specific type of biological network under contrasting environmental conditions.