Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA via modulation of the production of anti-cyclic citrullinated peptide antibodies or citrullinated antigens. © 2004 BioMed Central Ltd.
CITATION STYLE
Vossenaar, E. R., Zendman, A. J. W., & van Venrooij, W. J. (2004). Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis. Arthritis Research and Therapy, 6(1), 1–5. https://doi.org/10.1186/ar1027
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