Abstract
It has been demonstrated that caffeine enhances the cytocidal effect of certain anticancer agents. The inhibition of DNA repair by caffeine has been considered to be one mechanism that enhances the cytocidal effect of such agents. The present study was conducted to clarify whether caffeine increases the effect of cisplatin (CDDP) on human lung adenocarcinoma cell line (PC9). CDDP concentrations used in this study were 1.0, 2. 0
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Yoshinobu, O., akae, I., Toshiaki, F., Jun-ichi, K., Hiroyuki, M., & Sokichi, O. (1990). The Combination Effect of Caffeine and Cisplatin on a Human Lung Cancer Cell Line. Japanese Journal of Lung Cancer, 30(3), 341–349. https://doi.org/10.2482/haigan.30.341
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