Population genetics of 14 ethnic groups using phenotypic data from VNTR loci.

6Citations
Citations of this article
3Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Population genetic studies were performed using five VNTR loci (D2S44, D4S163, D14S13, D17S79, D18S27). The populations examined were Caucasian (Australia, Brazil and U.S.A.), Australian aborigine, Chinese, Amerindian (Cheyenne, Maya, Navajo, Pima, Tobas/Wicnis), North American Black, North American Hispanic (California, Miami, New York, Texas). The overall size range of the alleles for these loci, in PstI-digested DNA, was the same in all populations. The major difference among populations was the relative frequency of particular groups of alleles. These differences were small among similar ethnic groups, while sometimes varying several fold among some of the more distinct populations. However, groups of alleles that were rare in the major ethnic groups (Caucasian, Black, Chinese) were also rare in the other populations. The frequency databases generated by typing individuals for 4 loci were used to compare the random DNA profile frequencies among populations. The results show that the estimated frequency of any 4 locus profile is very low in all populations examined (e.g., median value < 10(-8)). Analysis of relative genetic similarity among populations was used to create the most likely clustering of these ethnic groups. Results show an uncanny similarity between the clusters generated and genetic distance measurements obtained with traditional calculations of conventional genetic markers.

Cite

CITATION STYLE

APA

Balazs, I. (1993). Population genetics of 14 ethnic groups using phenotypic data from VNTR loci. EXS, 67, 193–210. https://doi.org/10.1007/978-3-0348-8583-6_16

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free