Evaluating the biological activity and effects on human health of fish oil and its omega-3 fatty acids

Abstract

This chapter reviews the background, chemistry and specific efficacy of fish oils, specifically ω-3 fatty acids in the treatment and prevention of disease. Epidemiologic evidence appears strong showing its protective effects, although clinical trials with definitive data are still deficient. The mechanism by which ω-3 fatty acids may work on the nervous system and its anti-inflammatory effects are presented. Efforts should be made to ensure dietary intakes should provide sufficient amounts of these essential fatty acids through moderate intake of cold water fatty fish. © 2008 Humana Press Inc.