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Radiolabeling of DNA by Nick Translation

  • Mathew C
Humana Press, (2003), 257-262
DOI: 10.1385/0-89603-064-4:257
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Abstract

Nick translation is the name given to a reaction that is used to replace cold nucleoside triphosphates in a double-stranded DNA molecule with radioactive ones (1,2). Free 3′-hydroxyl groups are created within the unlabeled DNA (nicks) by deoxyribonuclease 1...

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Mathew, C. G. P. (2003). Radiolabeling of DNA by Nick Translation. In Nucleic Acids (pp. 257–262). Humana Press. https://doi.org/10.1385/0-89603-064-4:257

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