A comparative study on langerhans cells in lymph nodes with dermatopathic lymphadenopathy and histiocytosis X cells

Abstract

It was elucidated that the majority of DC were LC which were positive for CD1a, but negative for PCNA, and possessed BG in the lymph nodes with DPL. On the other hand, HCX cells were almost always positive for PCNA. From this point of view, it can be speculated that LC in the lymph nodes of the DPL are non dividing mature cells and migrate from the skin lesion. HCX cells which were positive for CD4 may be more immature cells than LC in DPL, and may be pathological cells which can divide in the foci.