Amorphous APIs: Improved release, preparation, characterization

Abstract

Producing Amorphous Active Pharmaceutical Ingredients offers an enhanced drug release that is caused by the increase in its dissolution rate. This improvement enables higher bioavailability and bioactivity of such solid APIs. Possibilities to control the drug release and its bioactivity offer new opportunities to design more effective and stable medications. This chapter is a general introduction to Amorphous APIs and most commonly discussed production and characterization methods.