Steroid/triterpenoid functional molecules based on "click chemistry"

Abstract

This Focus Review highlights the design and synthesis of various functional molecules based on steroid/triterpenoid as building blocks through the copper-catalyzed azide-alkyne cycloaddition (CuAAC) "click" reaction, as well as their applications in bioactivity, recognition, and assembly. This method shows great promise to allow us to develop novel molecules with characteristic functions using the CuAAC "click" reaction. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.