Relationship of periodontal disease and tooth loss to glucose metabolism disorder: The Ohasama study

Abstract

The purpose of this study was to examine the association of periodontal disease and tooth loss with glucose metabolism disorder. Cross-sectional data on 507 individuals aged ≥55 years old were obtained from the general population of Ohasama, a rural community in Japan. Periodontal status was examined using probing depth (PD) and clinical attachment loss (CAL). Subjects with at least 10 teeth were divided into two groups based on mean PD and CAL, with cut-off of 2.0 mm and 2.5 mm, respectively. The other subjects with 0-9 teeth were defined as multiple tooth loss group. Glucose metabolism disorder was defined as serum glycosylated hemoglobin (HbA1c) level of at least 5.8% and/or the use of medication for diabetes. Multivariate logistic regression analysis indicated that CAL ≥ 2.0 mm and multiple tooth loss were independently associated with the presence of glucose metabolism disorder. Our results suggest that a history of periodontal disease assessed by CAL and multiple tooth loss may be associated with an increased risk of glucose metabolism disorder.