Tuberculosis Diagnosis — Time for a Game Change

Abstract

The effective treatment of tuberculosis is a lifesaving intervention. The global scale-up of tuberculosis therapy has averted 6 million deaths over the past 15 years, making it one of the greatest public health interventions of our lifetime.1 Unfortunately, by the time most patients are treated, they have already infected many others.2 This failure to interrupt transmission fuels the global epidemic so that every year there are more new cases of tuberculosis than in the previous year.1 National tuberculosis programs are particularly challenged by multidrug-resistant tuberculosis. Globally, fewer than 2% of the estimated cases of multidrug-resistant disease are reported to the . . .