This paper looks at ion channels as an example of the pharmacologist's stock in trade, the action of an agonist on a receptor to produce a response. Looked at in this way, ion channels have been helpful because they are still the only system which is simple enough for quantitative investigation of transduction mechanisms. A short history is given of attempts to elucidate what happens between the time when agonist first binds, and the time when the channel opens. © 2006 Nature Publishing Group All rights reserved.
CITATION STYLE
Colquhoun, D. (2006, January). Agonist-activated ion channels. British Journal of Pharmacology. https://doi.org/10.1038/sj.bjp.0706502
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